In 1962 Belle Baruch received a diagnosis of cancer. She died in 1964 at the age of 64, with Ella Severin and her father at her bedside.
After her death, Bernard Baruch rejected the idea of naming Belle's foundation after him, and it was agreed that it be called the Belle W. Baruch Foundation.
Today the Belle W. Baruch Foundation owns Hobcaw Barony and makes it available to researchers at South Carolina's universities, as provided in Belle's will.
There are two research facilities on the property: Clemson University's Belle W. Baruch Institute of Coastal Ecology, established in 1968, and the University of South Carolina's Belle W. Baruch Institute of Marine and Coastal Sciences, founded in 1969.